May and July 2015/University of Haifa, Israel, etc./International Journal of Medicinal Mushrooms
Text/Wu Tingyao
Clinical complications associated with diabetes may include cardiovascular autonomic neuropathy, neuropathy, nephropathy, anemia, and weakened immunity. Too much glucose in the blood will destroy red blood cells; the hyperglycemia environment triggers a large number of free radicals to proliferate, which will push the white blood cells towards apoptosis. A joint study by Israeli and Ukrainian scholars has shown that the submerged culture mycelium powder ofغانوديرما لوكيدوم at a certain high dose can simultaneously improve these two problems and improve the health of diabetic animals.
غانوديرما لوكيدوم protects red blood cells and prevents anemia in diabetes.
Anemia is one of the common complications of diabetes. High concentration of blood sugar can cause erythrocyte membrane degeneration, which greatly shortens the lifespan of erythrocytes, and then causes anemia, which makes patients difficult to breathe or feel weak and tired because of tissue cellular hypoxia.
According to a joint study conducted by University of Haifa in Israel and Ivan Franko National University of Lviv in Ukraine, the submerged culture mycelium powder ofغانوديرما لوكيدوم can not only fight anemia but also lower blood sugar.
The researchers first injected rats with a synthetic antibiotic (streptozotocin) to destroy their pancreatic islet cells, causing them to form type 1 diabetes, and then orally treated them withغانوديرما لوكيدوم submerged culture mycelium powder (1 g/kg/day).
Two weeks later, compared with untreated diabetic rats, theغانوديرما لوكيدوم group not only significantly reduced the blood glucose index and glycosylated hemoglobin concentration but also had more red blood cells in the blood. The red blood cells were less prone to “hemolytic reaction” (referring to abnormal decomposition and death of red blood cells). Meanwhile, the concentration of fetal hemoglobin is relatively normal (this index will increase during anemia), and the body’s ability to produce red blood cells is greatly improved.
Long-term high blood sugar will harm both red blood cells and white blood cells. A high blood sugar environment will promote the production of a large number of free radicals (such as nitric oxide), resulting in an increase in the number of white blood cells (أي. immune cells with immune activity) apoptosis, which in turn leads to a decline in immunity. لذلك, the research team also observed the protective effect ofغانوديرما لوكيدوم mycelium on white blood cells through animal experiments.
When type 1 diabetic rats ateغانوديرما لوكيدوم mycelium powder for two weeks (dose: 1 g/kg/day), the activity of nitric oxide synthase in the body decreased while the metabolites of nitric oxide decreased. في نفس الوقت, the number of white blood cells and the ratio of apoptotic protein (p53) and antiapoptotic protein (Bcl-2) in white blood cells are also relatively close to those in normal rats. These results indicate that under the environment of high blood sugar in vivo, the submerged culture mycelium powder ofغانوديرما لوكيدوم can reduce the production of reactive nitrogen species and protect white blood cells.
In addition toغانوديرما لوكيدوم, the researchers also observed the anti-anemia, hypoglycemic, anti-reactive nitrogen species and anti-apoptotic effects of the submerged culture mycelium powder ofAgaricus brasiliensis. Under the same animal model, the same dosage, and the same time conditions, although the submerged culture mycelium powder ofAgaricus brasiliensis also has a good effect, it is a pity that its performance is slightly weaker than that ofغانوديرما لوكيدوم.
لكن, no matter whether it is the submerged culture mycelium powder ofغانوديرما لوكيدوم orAgaricus brasiliensis, both have no adverse effects on the blood sugar, red blood cells or white blood cells of normal rats.
The above research results have been published in the “International Journal of Medicinal Mushrooms” in 2015 in two issues.
[مصدر]
1. vitak TY, وآخرون. The Effect of the Medicinal Mushrooms Agaricus brasiliensis and Ganoderma lucidum (Higher Basidiomycetes) on the Erythron System in Normal and Streptozotocin-Induced Diabetic Rats. Int J Med Mushrooms. 2015;17(3):277-86.
2. Yurkiv B, وآخرون. The Effect of Agaricus brasiliensis and Ganoderma lucidum Medicinal Mushroom Administration on the L-arginine /Nitric Oxide System and Rat Leukocyte Apoptosis in Experimental Type 1 Diabetes Mellitus. Int J Med Mushrooms. 2015;17(4):339-50.
نهاية
نبذة عن الكاتبة/ م. وو تينغياو
Wu Tingyao has been reporting on first-hand Ganoderma information since 1999. هي مؤلفة الشفاء بالجانوديرما (نشرت في دار النشر الطبية الشعبية في أبريل 2017).
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★ تمت كتابة النص الأصلي لهذه المقالة باللغة الصينية بواسطة Wu Tingyao وترجمها إلى الإنجليزية بواسطة Alfred Liu. إذا كان هناك أي اختلاف بين الترجمة (English) والأصل (الصينية), يجب أن تسود الصينية الأصلية. إذا كان لدى القراء أي أسئلة, يرجى الاتصال بالمؤلف الأصلي, آنسة. وو تينغياو.
