June 23, 2011 / Kobe Pharmaceutical University / Phytotherapy Research
Text/ Wu Tingyao
Nasal obstruction, itchy nose, sneezing and runny nose are common symptoms of “allergic rhinitis”, and pollen is one of the allergens of allergic rhinitis. During the flowering season, someone enjoys the flowers, but someone hates his nose. Perhaps eatingGanoderma lucidum patiently can make allergic noses less allergic.
A research report published by the Department of Pharmacology of Kobe Pharmaceutical University in Japan in “Phytotherapy Research” in 2011 used guinea pigs as experimental subjects. The researchers first made guinea pigs inhale pollen intensively within a week to form an allergic physique. After a week interval, they made the guinea pigs inhale pollen once a day to induce nose allergies. And, two days before the guinea pigs “inhale pollen”, the researchers began to feed the guinea pigsGanoderma lucidum fruiting body powder (Containing 7.5% chitin and 40%Ganoderma lucidum polysaccharide) at a dose of 100 ou 1,000 mg per kilogram of body weight per day for eight weeks.
It was found that compared with the guinea pigs that were not protected byGanoderma lucidum, the group of guinea pigs that hadGanoderma lucidum had significantly reduced their nasal congestion symptoms from the fifth week (high doses lead to better results); the number of sneezes was also reduced (the effect of low doses is similar to that of high dose).
Even if the researchers used leukotriene (one of the inflammatory mediators that cause allergic reactions) to aggravate the irritation in the later stage of the experiment, the group that ate high-doseGanoderma lucidum had been less affected on nose breathing.
Experiments also found that after stopping the use ofGanoderma lucidum, if the guinea pigs are continuously exposed to allergens, the effect ofGanoderma lucidum in reducing nasal congestion still exists in the first week, but by the second week, the situation of nasal congestion is as worse as that of those guinea pigs who did not eatGanoderma lucidum.
In addition, takingGanoderma lucidum for a short period of time is not effective, because researchers have tried to feed guinea pigs with rhinitis symptoms for one and a half months with a high dose of Ganoderma for a week, butGanoderma lucidum has not been able to improve the nasal congestion of the guinea pigs.
This research reminds us thatGanoderma lucidum can improve allergic rhinitis, but such improvement cannot be done overnight.Ganoderma lucidum will show its effects when taken for a certain period of time and continue to be effective when taken uninterruptedly. In this experiment, it was “not” observed thatGanoderma lucidum can reduce the amount of IgE, which shows thatGanoderma lucidum has an obvious effect of “inhibiting inflammation” in the improvement of allergic symptoms in the initial stage. It may take more time to adjust physical fitness throughGanoderma lucidum, and it is better to stay away from allergens.
As for why researchers choose guinea pigs for experiments? Because they do not breathe with their mouths, the accuracy of the experimental results is greatly improved.
[Source] Mizutani N, et autres. Effect of Ganoderma lucidum on pollen-induced biphasic nasal blockage in a guinea pig model of allergic rhinitis. Phytother Res. 2012 Mar;26(3):325-32. est-ce que je: 10.1002/ptr.3557. Epub 2011 juin 23.
FIN
À propos de l'auteur/Mme. Wu Tingyao
Wu Tingyao has been reporting on first-handGanoderma lucidum information since 1999. Elle est l'auteur deGuérir avec Ganoderma (publié dans The People's Medical Publishing House en avril 2017).
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★ Le texte original de cet article a été rédigé en chinois par Wu Tingyao et traduit en anglais par Alfred Liu.. S'il y a une divergence entre la traduction (English) et l'original (Chinois), le chinois original prévaudra. Si les lecteurs ont des questions, veuillez contacter l'auteur original, MS. Wu Tingyao.
