Une étude publiée dans « Pharmacological Research » par le Laboratoire clé d'État de recherche sur la qualité de la médecine traditionnelle chinoise de l'Université de Macao. (auteur correspondant du rapport de recherche) et de nombreuses institutions de recherche nationales en août 2020 trouvé:
Compléter les souris avec de l'huile de spores de Ganoderma lucidum (800 mg/kg) chaque jour pour 27 consecutive days can significantly improve the phagocytic ability of macrophages and the toxicity of natural killer cells (Cellules NK).
Macrophages and natural killer cells are the protagonists of the “innate immune response”. Their role in the immune system is like the police soldiers patrolling and maintaining order in the human world. They can be said to be at the forefront of defense against various bacteria, virus, and cancer cells.
Donc, the response ability of macrophages and natural killer cells will increase with the supplement of spore oil, which can increase the chance of the immune system to kill various “invisible enemies”.
Why does spore oil improve immunity? It is closely related to intestinal bacteria.
The intestine is distributed with numerous immune cells and also contains all kinds of bacteria. Different dietary habits will strengthen or weaken different types of intestinal bacteria, and different structural ratios of intestinal flora and metabolites produced by different types of intestinal bacteria will affect the direction and level of the immune response.
According to the analysis of this research report, after mice have consumed spore oil for a period of time, the composition and metabolites of their intestinal flora will change, such as:
The increase of beneficial bacteria such as Lactobacillus, the decrease of harmful bacteria such as Staphylococcus and Helicobacter, and the change of more than a dozen species of metabolites such as dopamine and L-threonine in quantity.
These changes are beneficial to promote the phagocytosis of macrophages and enhance the killing ability of natural killer cells.
In the past few years, many studies have proved that the immune enhancement effect of Ganoderma lucidum fruiting body extract and spore powder is related to the regulation of intestinal flora and its metabolites. Nowadays, research has finally made up the gap in this aspect of spore oil.
Although increasing the activity of macrophages and natural killer cells can increase the defense level of the innate immune response, the formation of a complete and dense immune network also requires the support of other front-line sentinels (such as neutrophils and dendritic cells) and acquired immunity response members (such as T cells, Cellules B et anticorps).
Since the extract, spore powder and spore oil of Ganoderma lucidum have their own advantages in regulating immunity, why not simultaneously use them to maximize the chance of repelling the “invisible enemy”?
[Data Resource] Xu Wu, et autres. An integrated microbiome and metabolomic analysis identifies immunoenhancing features of Ganoderma lucidum spores oil in mice. Pharmacol Res. 2020 Août;158:104937. est-ce que je: 10.1016/j.phrs.2020.104937.
À propos de l'auteur/Mme. Wu Tingyao
Wu Tingyao rapporte des informations de première main sur Ganoderma lucidum depuis 1999. She is the author of “Ganoderma lucidum: Ingenious Beyond Description” (publié dans The People's Medical Publishing House en avril 2017).
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